Health Condition 1: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: OPIOID FREE ANAESTHESIA: premedication with lidocaine 1.5 mg/ kg IV, magnesium sulfate 40 mg/kg (in 100 ml of saline without exceeding 2.5 g), ketamine 25 mg IV and dexamethasone 0.1 mg
Sponsors
NORTH DMC MEDICAL COLLEGE AND HINDU RAO HOSPITAL
NORTH DMC MEDICAL COLLEGE AND HINDU RAO HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I and II 2. BMI -18-25 3. Undergoing laparoscopic cholecystectomy 4. Written informed consent
Exclusion criteria
Exclusion criteria: • history of allergy to any drug used for OFA or CGA; • history of alcohol, opioid or drug abuse; • chronic pain • psychiatric illness; • patients undergoing surgery with planned regional anesthesia, • patients with iatrogenic surgical complications such as bowel, ureter or bladder injuries. • Duration of surgery exceeding 90 minutes. • pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the intraoperative need to administer opioids for adequate intraoperative analgesia.Timepoint: 1) INTRAOPERATIVE 2) POSTOPERATIVE TILL 48 HRS AFTER THE SURGERY | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Occurrence of intra-operative complications e.g. hypotension, hypertension, tachycardia and bradycardia. 2. Mean alveolar concentration (MAC in %) of isoflurane used in both groups. 3. Pain intensity (assessed using the Numerical Rating scale) 4. Need for opioids for pain relief within the first 48 h of surgery; 5. Patient satisfaction (assessed on the Quality of Recovery-40 [QoR-40] questionnaire) at 24 h and 48 h postoperation Timepoint: intra-operative & post operative period (24 & 48 hrs) | — |
Countries
India
Contacts
Public ContactDR SHWETA DHIMAN
NORTH DMC MEDICAL COLLEGE AND HINDU RAO HOSPITAL
Outcome results
None listed