Health Condition 1: N179- Acute kidney failure, unspecified
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
International Society of Nephrology
Eligibility
Inclusion criteria
Inclusion criteria: Children of age group 6 months-18 years admitted in a general PICU and having AKI at admission or developing AKI within 7 days of PICU admission as per the KDIGO criteria, with or without requirement of renal replacement therapy.
Exclusion criteria
Exclusion criteria: Pre-existing CKD, Previous history of AKI, AKI due to primary renal disorders like glomerulonephritis, hemolytic uremic syndrome, obstructive uropathy, congenital anomaly of kidney and urinary tract etc and Not willing to give consent/not expected to follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of critically ill children, admitted with AKI or developing AKI within 7 days of admission in general PICU of developing country, developing CKD on follow upTimepoint: at 3 months and at 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Association of severity of Acute kidney injury and etiology of Acute kidney injury with short term and medium-term outcomes and outcomes at the end of study periodTimepoint: at hospital discharge, at 1 month, at 3 months and at 1 year;Predictive ability of serial urinary Neutrophil Gelatinase Associated Lipocalin levels of subsequent incidence of Acute kidney disease / Chronic kideny disease on follow upTimepoint: day 1 of Acute kidney injury, day 30 and at 3 months;Proportion of children, admitted with Acute kidney injury or developing Acute kidney injury within 7 days of admission in general PICU of developing country, developing transient Acute kidney injury, persistent Acute kidney injury and Acute kidney disease on follow upTimepoint: 2 days, 7 days, 3 months;Proportion of patients developing albuminuria and ambulatory hypertension at 3 months and 1 yearTimepoint: 3 months, 1 year | — |
Countries
India
Contacts
Public ContactDr Deblina Dasgupta
Institute of Child Health Kolkata
Outcome results
None listed