Health Condition 1: C50-C50- Malignant neoplasms of breast
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients having breast cancer planned for anthracycline based chemotherapy and have normal LA and LV function at baseline.
Exclusion criteria
Exclusion criteria: 1.Patients with previously diagnosed cardiovascular disease including valvular heart disease, ischemic heart disease, previous cardiac surgery, or percutaneous interventions 2.Seriously ill patients, patients with life expectancy less than 1 year 3.Patients with poor window, unable to lie down or pain at local site prohibiting detailed echocardiographic study 4.Patients with irregular rhythms including atrial fibrillation, frequent VPCs 5.Patients undergoing other treatments like radiotherapy 6.Patients with other serious comorbidities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left atrial strain(%)Timepoint: Before & 3, 6 , 9 months after Anthracycline-based chemotherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Other echocardiographic findingsTimepoint: Before & 3, 6 , 9 months after Anthracycline-based chemotherapy | — |
Countries
India
Contacts
Kasturba Medical College, Manipal Academy of Higher Education, Manipal