Health Condition 1: J22- Unspecified acute lower respiratory infection
Conditions
Interventions
None listed
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who complied with the 2012 Berlin definition diagnostic criteria for moderate to severe ARDS, including P/F 2. Patient >18 years of age.
Exclusion criteria
Exclusion criteria: 1. patients 2. pregnancy 3. chest trauma or bandaging of chest wall 4. thoracic deformity 5. pneumothorax 6. massive pleural effusion 7. h/o pulmonary alveolar disease 8. severe haemodynamic abnormalities 9. severe heart failure 10. acute coronary syndrome 11. patient undergoing extracorporeal membrane oxygenation 12. New pulmonary infection 13. Pulmonary edema 14. fat, air, amniotic fluid embolism 15. abdominal hypertension 16. Endotracheal tube displacement 17. Lobar collapse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the ventilator induced lung injury as assessed by reduction in the PF ratio by 20% on first 7 days of mechanical ventilationTimepoint: To evaluate the ventilator induced lung injury as assessed by reduction in the PF ratio by 20% every day on first 7 days of mechanical ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| All cause 28 days mortality. Change in bronchial aspirate interleukin 6 from baseline as assessed on day 1 & day 5 of mechanical ventilation. Change in LUS from baseline as assessed on first 7 days of mechanical ventilation. Timepoint: 7days & 28 days | — |
Countries
India
Contacts
Public Contactdr pradeep bhatia
AIIMS JODHPUR
Outcome results
None listed