Use of different doses of IV dexamethasone to prolong the post-operative pain relief in patients undergoing surgery below the umbilicus under spinal anesthesia

A comparative study of analgesic efficacy of two different doses of IV Dexamethasone for prolongation of postoperative analgesia in patients undergoing infraumbilical surgeries under spinal anesthesia.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053640

Enrollment

Registered

2023-06-07

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: IV Dexamethasone: Comparative efficacy of two different doses of Dexamethasone for prolongation of post operative analgesia. (0.1mg/kg and 0.2mg/kg) Control Intervention1: IV Dexamethas

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA 1 or 2 2. Infraumbilical surgeries 3. Spinal anesthesia

Exclusion criteria

Exclusion criteria: 1. Febrile 2. Emergency surgery 3. Paediatric 4. Present or history of peptic ulcer disease 5. Glaucoma 6. Diabetes mellitus 7. Established chronic renal failure 8. Pre-existing Hepatic diseases 9. Pregnant 10. surgeries expected to last more than 3 hours 11. Failure of spinal anesthesia 12. Patients on intravenous steroids.

Design outcomes

Primary

Measure	Time frame
To compare perioperative doses of IV Dexamethasone for prolongation of postoperative analgesia in patients undergoing infraumbilical surgeries under spinal anesthesiaTimepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440	—

Secondary

Measure	Time frame
To determine the efficacy of different doses of intravenous Dexamethasone in reducing the incidence of nausea and vomiting after infraumbilical surgeries under spinal anesthesia.Timepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440;To determine the efficacy of different doses of intravenous Dexamethasone in reducing the incidence of shivering after infraumbilical surgeries under spinal anesthesia.Timepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440;To determine the efficacy of different doses of intravenous Dexamethasone in reducing the number of opioid analgesics used postoperatively after infraumbilical surgeries under spinal anesthesia.Timepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440	—

Measure

Time frame

To determine the efficacy of different doses of intravenous Dexamethasone in reducing the incidence of nausea and vomiting after infraumbilical surgeries under spinal anesthesia.Timepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440;To determine the efficacy of different doses of intravenous Dexamethasone in reducing the incidence of shivering after infraumbilical surgeries under spinal anesthesia.Timepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440;To determine the efficacy of different doses of intravenous Dexamethasone in reducing the number of opioid analgesics used postoperatively after infraumbilical surgeries under spinal anesthesia.Timepoint: in minutes 0 ,15,30,60,120,360,720,1080,1440

—

Countries

India

Contacts

Public ContactAashish Kiraan B

PSG IMSR

drprasanth1979@yahoo.co.in9943775657

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026