By doing this study, weâ??re trying to find whether Zinc, which is a mineral supplement, anti inflammatory and increases the insulin secretion and decreases insulin requirement, can help decrease the disease activity, thereby reducing the complications of the disease and insulin requirement.

Effect of zinc supplementation on glycemic control in children with type 1 diabetes mellitus (T1DM): A randomized, double-blind controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053634

Enrollment

Registered

2023-06-07

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E108- Type 1 diabetes mellitus with unspecified complications

Interventions

Intervention1: Standard therapy with zinc (oral zinc sulphate 20mg daily for 12 weeks): Standard therapy with zinc (oral zinc sulphate 20mg daily for 12 weeks) Control Intervention1: Standard therapy

Eligibility

Inclusion criteria

Inclusion criteria: Type 1diabetes mellitus children diagnosed as per WHO criteria aged 3 to 18 years with minimum duration from diagnosis of 6 months

Exclusion criteria

Exclusion criteria: Patients who were treated with zinc for other illnesses in the last 3 months.

Design outcomes

Primary

Measure	Time frame
To assess the effect of daily zinc (20mg) supplementation on change in HbA1c level.Timepoint: 4 weeks, 8 weeks, 12 weeks	—

Secondary

Measure	Time frame
1)To analyze the effect of zinc supplementation on the antioxidant activity 2)To analyze the effect of zinc supplementation on autoantibodies in Type 1 DM 3)To analyze the effect of zinc supplementation on c-peptide levels 4)To analyze the effect of zinc supplementation on lipid profile Timepoint: 4 weeks, 8 weeks, 12 weeks	—

Countries

India

Contacts

Public ContactVijayalaxmi Yeresheeme

JIPMER, Puducherry

dillikumar14@gmail.com9566028886

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026