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Influence of dexmedetomidine drug in scalp(head) block with ropivacaine drug 0.25% for obtaining effect of nociceptive(pain) and haemodynamic responses to skull pin placement in neurosurgical patients undergoing craniotomy surgery.

Influence of dexmeditomidine in scalp block with ropivacaine 0.25% for attenuation of nociceptive and haemodynamic responses to skull pin placement in neurosurgical patients undergoing craniotomy:A prospective randomized comparative study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053603
Enrollment
60
Registered
2023-06-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: R298- Other symptoms and signs involvingthe nervous and musculoskeletal systems Health Condition 3: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: scalp block for skull pin placement in craniotomy.: Group A-ropivacaine o.25% Intraoperativevely starting frome pre surgical baseline values to time interval of 5-15 mins followed by h

Sponsors

mahatma gandhi hospital and medical college
Lead Sponsor
mahatma gandhi hospital medical college
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Age:18-65 ASA 1 & 2 Scheduled for elective neurosurgical procedures. Agreed for written & informed consent. Requiring mayfield skull pin holder.

Exclusion criteria

Exclusion criteria: Uncontrolled hypertensive patients. Pre operative bradycardia. Ischemic heart disease. Cardiac arrhythmia. Hepatic and renal disease. Allergy to study drugs. Past history of craniotomy. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
To analyse and compare the change in HR,using lead II of ECG,systolic bp,diastolic BP at different time points after skull pin placement from baseline in both the groups using invasive blood pressure monitoring.Timepoint: 15 minutes from baseline to 1 hour, then half an hour till 4 hours—

Secondary

MeasureTime frame
The secondary outcome of the study will be on intraoperatively hemodynamic monitoring including blood pressure, MAP,HR and SPO2.Timepoint: 5 Min observation till 15 mins,then 15 mins observation till 1 hour,then half n hour observation for 4 hours.—

Countries

India

Contacts

Public ContactDr Nitesh Dahiya

mahatma gandhi medical college,jaipur.

Doctorprachi.verma@gmail.com9829191038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026