Health Condition 1: M171- Unilateral primary osteoarthritisof knee
Conditions
Interventions
Intervention1: Adductor canal block, Ropivacaine, Dexamethasone, Dexmedetomidine: Ultrasound guided adductor canal block with 30 ml of 0.5% Ropivacaine along with Dexamethasone 4 mg & Dexmedetomidine
Sponsors
Tata Main Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective primary unilateral total knee arthroplasty under subarachnoid block ASA grades I-III
Exclusion criteria
Exclusion criteria: Patients refusing to participate in the study History of allergy to local anesthetics Patients with coagulopathy or infection at the site of block Patients with psychiatric illness or cognitive dysfunction who cannot use the patient-controlled analgesia (PCA) Patients having neuromuscular deficits, severe COPD, renal deficiency, severely compromised cardiovascular status Patients with body mass index (BMI) of > 35 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total opioid (Morphine) consumption in the first 24 hours postoperativelyTimepoint: Total opioid (Morphine) consumption in the first 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Episodes of hypotension, bradycardia and desaturation Timepoint: In the first 48 hours postoperatively;Functional outcome by TUG test (in seconds)Timepoint: At 48 hours postoperatively ;NRS pain scoresTimepoint: At 3, 6, 12, 18, 24, 30, 36, 42 and 48 hours postoperatively, both at rest and with movement;Opioid (Morphine) consumptionTimepoint: At 48 hours postoperatively;Quadriceps muscle strength assessment by Manual Muscle Testing score (MMT) Timepoint: At 24 and 48 hours postoperatively;Ramsay sedation score Timepoint: at 3, 6, 12, 18, 24, 20, 36, 42 and 48 hours postoperatively;Time to first requirement of rescue analgesia Timepoint: Not Applicable | — |
Countries
India
Contacts
Public ContactRavi Kant
Tata Main Hospital
Outcome results
None listed