Health Condition 1: L209- Atopic dermatitis, unspecified
Conditions
Interventions
Intervention1: not applicable: not applicable
Sponsors
Society for eczema Studies
Post Graduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: (a)Age at presentation equal to or more than 18 years (b)Active atopic dermatitis diagnosis of which shall be made on 2 grounds 1. Fulfilment of Hanifin and Rajkaâ??s original criteria 2. Expert opinion where 3 independent eczema experts decide unanimously on the diagnosis of adult AD
Exclusion criteria
Exclusion criteria: (a)Pregnancy and lactation (b)Any immunocompromised state (c)Patients with a history or physical exam suggestive of other causes of eosinophilia common in our settings-helminthic infection, DRESS(drug reaction with eosinophilia and systemic symptoms), bullous pemphigoid, chronic bullous disease of childhood , fungal infections, chronic pancreatitis, primary gastrointestinal eosinophilic disorders including inflammatory bowel disease, eosinophilic esophagitis, coeliac diseases, rheumatological disease-systemic lupus erythematosus, eosinophilic fasciitis (Shulman disease) , vasculitis - polyarteritis nodosa and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome), rheumatoid arthritis and acute and chronic eosinophilic pneumonia (that includes Loeffler syndrome, sarcoidosis, allergic bronchopulmonary aspergillosis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Classification of clinical characteristics of adult patients having AD into the following four subgroups as mentioned below 1.High IgE & Eosinophilia 2.Normal IgE & Eosinophilia 3.High IgE and Normal Eosinophils 4.Normal IgE and Normal Eosinophils Timepoint: 1.5 years | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-4 levels in the different subgroupsTimepoint: 1.5 years | — |
Countries
India
Contacts
Public ContactDr Manavi Gupta
Post Graduate Institute of Medical Education and Research
Outcome results
None listed