Comparison between anaesthesia with and without opioids in oral cancer surgeries

Opioid free general anaesthesia versus opioid inclusive general anaesthesia for oral cancer surgeries: A randomised double blind study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/06/053578

Enrollment

454

Registered

2023-06-06

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Opioids free general anaesthesia group: In group K, General anaesthesia will be induced with intravenously ketamine 0.5mg/kg diluted in 10 ml saline, propofol 2.0 mg/kg, rocuronium 0.5

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients of ASA-1, 2 and 3 2 Patients scheduled for surgeries of oral cavity malignancy

Exclusion criteria

Exclusion criteria: 1 Patients with known history of study drug allergy 2 Renal or hepatic impairment 3 Moderate to severe cardiovascular disease 4 Patients taking drugs for chronic pain

Design outcomes

Primary

Measure	Time frame
Post operative pain and rescue analgesicsTimepoint: All the parameters will be recorded post extubation , 30 minutes, 60 minutes, 90 minutes, 2, 3, 4, 6, 12 and 2 hours post operatively	—

Secondary

Measure	Time frame
Post operative nausea and vomiting incidence and severity, length of PACU stay, patient satisfaction and any adverse eventsTimepoint: All the parameters will be recorded post extubation , 30 minutes, 60 minutes, 90 minutes, 2, 3, 4, 6, 12 and 2 hours post operatively	—

Countries

India

Contacts

Public ContactDr Prakash K Dubey

IGIMS, Patna

pkdubey@hotmail.com9430511851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026