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Effect of intravenous lignocaine in preventing post operative sorethroat, an intervention study

EFFICACY AND SAFETY OF PERI-OPERATIVE INTRAVENOUS LIGNOCAINE IN PREVENTING THE POST OPERATIVE SORE THROAT – A PLACEBO CONTROLLED STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053564
Enrollment
288
Registered
2023-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: EFFICACY AND SAFETY OF PERI-OPERATIVE INTRAVENOUS LIGNOCAINE IN PREVENTING THE POST OPERATIVE SORE THROAT – A DOUBLE BLIND STUDY: After thorough pre-anaesthetic evaluation, patients wil
Grade II: Only the posterior extremity of the glottis was visible
Grade III: Only the epiglottis was visible and Grade IV: No recognisable structure was observed. Anaesthesia with isoflurane 1–1.25% in oxygen and air will be given to all patients. Sedation was asse

Sponsors

COMMAND HOSPITAL AIRFORCE BANGALORE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Patients of either gender, aged between 18 to 65 years, posted for surgeries requiring GA. - Patients belonged to ASA 1 and 2 will be included - Patients willing to participate in the study by obtaining the written informed consent

Exclusion criteria

Exclusion criteria: - Patients with abnormal coagulation profile or on anticoagulation therapy, severe anaemia, hypovolemia, shock, septicaemia and history of seizure disorder. - Allergy to the study drug. - Emergency surgeries - Smoker , prior history of sore throat - Patients who are on treatment with inhaled steroids for any condition

Design outcomes

Primary

MeasureTime frame
-Analysing the incidence of Post operative sore throat between lignocaine versus normal saline group. -Assessing the safety of peri operative intravenous lignocaine in preventing the incidence of sore throat. -Incidence of dysphagia and cough between lignocaine versus normal saline group Timepoint: specific time at which the outcome will be assessed/estimated i.e.IMMEDIATELY, 6 HR , 12 HR AND 24 HR—

Secondary

MeasureTime frame
Analysing the efficacy of peri operative intravenous lignocaine in preventing the incidence of sore throatTimepoint: estimated immediately, 6hours , 12 hours and 24 hours—

Countries

India

Contacts

Public ContactMANIMARAN P

COMMAND HOSPITAL AIRFORCE BANGALORE

mdsatish08@yahoo.in7829024442

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026