Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: Dexmedetomidine is Alfa2 receptor agonist
Dose 2microgram/kg iv infusion over 10 min
Intervention2: clonidine: Clonidine is Alfa2 receptor agonist
DOSE 1 microgram/kg
Sponsors
ARTI YADAV
Eligibility
Inclusion criteria
Inclusion criteria: ASA Physical status I and II
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. History of laryngeal or tracheal surgery or pathology. 3. History of Bronchial asthma, 4. History of smoking, alcohol addiction or drug abuse. 5. Patients with coexisting systemic illness, morbid obese patient, neurological or psychological disease, hepatic or renal dysfunction, endocrinal or metabolic disorder. 6. Patients with hypertensive heart disease or on antihypertensives, beta blockers or calcium channel blockers. 7. Patient with known hypersensitivity or drug allergies. 8. Age less than 18 or more than 60. 9. Basal heart rate less than 60 and patient with heart block or with conduction defect. 10. Active upper respiratory tract infections. 11. Patients with difficult airway MP grade III and IV. 12. Pregnant or lactating female
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To evaluate and compare the intraoperative hemodynamic parameter with intravenous dexmedetomidine and intravenous clonidine as premedication during laproscopic surgeries under general anaesthesia.Timepoint: vital monitoring was done at baseline ,1 min before premedication ,1 min after premedication,1 min before induction,1 min after induction,1 min before intubation ,1 min after intubation,2 min,4 min,6 min,8 min ,10 min ,1 min after CO2 insufflation,after 15 min,at 5 min time interval up to 90 min . | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate Side effects of intravenous dexmedetomidine and clonidine.Timepoint: 1 min after giving drugs,2min,4min,6min,8min 10 min at 5 min time interval up to 90 min . | — |
Countries
India
Contacts
Public ContactARTI YADAV
Swami vivekanand subharti university
Outcome results
None listed