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Spinal anaesthesia comparison with hyperbaric drug in lower limb orthopaedic surgeries

A COMPARATIVE EVALUATION BETWEEN INTRATHECAL ADMINISTRATION OF HYPERBARIC LEVOBUPIVACAINE AND HYPERBARIC LEVOBUPIVACAINE WITH CLONIDINE FOR DETERMINING THE DURATION OF ANALGESIA IN PATIENTS UNDERGOING LOWER LIMB ORTHOPAEDIC SURGERIES.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053562
Enrollment
50
Registered
2023-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V899- Person injured in unspecified vehicle accident

Interventions

Control Intervention1: Spinal anaesthesia with Hyperbaric levobupivacaine and hyperbaric levobupivacaine and clonidine: INTRATHECAL administration of hyperbaric levobupivacaine 3ml + Inj clonidine 30m

Sponsors

Rajarajeshwari medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective lower limb orthpaedic surgeries of either gender aged 20-50 years with American Society of Anaesthesiologists (ASA) I and II status under Spinal anaesthesia

Exclusion criteria

Exclusion criteria: Patients with low heart rate Known hypersensitivity to local anaesthetic drugs pregnant and lactating women patient refusal local site infection, Peripheral vascular disease Severe cardiovascular, respiratory ,hepatic and renal diseases, coagulation abnormalities, with previous spine surgeries and spine abnormalities

Design outcomes

Primary

MeasureTime frame
To compare the effect of adding 30 mcg Inj Clonidine to 0.5% Levobupivacaine(H) vs plain Inj Levobupivacaine 0.5% for lower limb orthopaedic surgeries under spinal anaesthesiaTimepoint: Duration of analgesia in the first 24 hours post surgery

Secondary

MeasureTime frame
To evaluate - Time of onset and duration of sensory and motor blockade. Regression of segments of motor and sensory blockade. Hemodynamic changesTimepoint: Intraoperative onset of motor and sensory blockade. Intra operative and Postoperative regression of motor and sensory blockade

Countries

India

Contacts

Public ContactDr Karthik G S

Rajarajeshwari medical college and hospital

drsowmyasharma@gmail.com9980891082

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026