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The use of intravenous lignocaine to reduce opioid consumption postoperatively and enhance recovery in posterior spine fusion surgeries

Effect of intravenous lignocaine on postoperative opioid consumption and recovery after posterior spine fusion surgeries - A randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053512
Enrollment
72
Registered
2023-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M47- Spondylosis

Interventions

Intervention1: Intravenous lignocaine: Group 1 patients will receive intravenous lignocaine 1.5 mg/kg bolus 2 minutes before intubation followed by 1 mg/kg/hr infusion till end of surgery. Control In

Sponsors

Pondicherry Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-60 years of either sex. 2. Patients belonging to American society of Anesthesiologist physical status1 and 2. 3. Patients undergoing posterior spine fusion surgeries under General anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients with allergy to local anaesthetic. 2. Patients undergoing spinal revision surgery . 3. Patients with bradycardia (HR 4. Patients with seizure disorders. 5. Patients with uncontrolled diabetes, hypertension, chronic kidney disease, active coronary artery disease and severe COPD and Asthma.

Design outcomes

Primary

MeasureTime frame
To determine the effect of intraoperative intravenous lignocaine infusion on postoperative opioid consumption during first 24 hrs after posterior spine fusion surgeries under general anaesthesia in 72 participants. OUTCOME VARIABLES: Postoperative opioid consumption Intraoperative opioid consumption VAS score in both the groups in first 24 hrs. Hemodynamic parameters (SBP, DBP & MAP) Quality of recovery using QOR â?? 15 scale Timepoint: 24 hrs—

Secondary

MeasureTime frame
1. To compare the postoperative VAS score in first 24 hrs in both the groups . 2. To compare the hemodynamic parameters (SBP, DBP & MAP) during the intraoperative period in both the groups. 3. To determine the quality of recovery using QOR â?? 15 scale after 24 hrs of surgery in both the groups. Timepoint: 24 hrs—

Countries

India

Contacts

Public ContactSivakumar S

Pondicherry Institute of Medical Science

siva85dr@gmail.com9944060676

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026