Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
None listed
Sponsors
Vishal Vishnu Tewari
Eligibility
Inclusion criteria
Inclusion criteria: All preterm neonates at and below 32 weeks period of gestation with moderate to severe RDS serially admitted to the NICU of Command hospital (WC), Chandimandir will be included in the study.
Exclusion criteria
Exclusion criteria: Neonates with major congenital anomalies, congenital heart diseases, gestation at and below 24 weeks or greater than 32 weeks, preterm neonates at and below 32 weeks with mild RDS not requiring intratracheal surfactant and neonates intubated at delivery for resuscitation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine short-term respiratory outcomes in preterm neonates at 32 weeks & below with respiratory distress syndrome (RDS) given intratracheal surfactant by less invasive surfactant administration (LISA) technique measured as duration of respiratory support in hours.Timepoint: To determine short-term respiratory outcomes in preterm neonates at 32 weeks & below with respiratory distress syndrome (RDS) given intratracheal surfactant by less invasive surfactant administration (LISA) technique measured as duration of respiratory support in hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine the required number of doses of surfactant per patient 2. To determine the failure of LISA technique 3. To determine the procedure success rate 4. Incidence of mortality, bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), patent ductus arteriosus (PDA), necrotizing enterocolitis (NEC) & retinopathy of prematurity (ROP)Timepoint: By day of discharge from the hospital | — |
Countries
India
Contacts
Public ContactVishal Vishnu Tewari
Command Hospital (WC) Chandimandir
Outcome results
None listed