Health Condition 1: K740- Hepatic fibrosis
Conditions
Interventions
None listed
Sponsors
Mahatma Gandhi Medical Colllege and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Chronic liver disease patient posted for liver transplant Age (18-65)
Exclusion criteria
Exclusion criteria: Acute liver failure patients Paediatric patient posted for liver transplant ( age 0-18) Patients posted for combined liver and kidney transplant Patients with recent history of cerebral bleed ( Recurrent cardiac arrhythmia Reduced systolic ventricular function (LVEF Chronic lung disease Intraoperative use of vasopressor prior to start of study Extreme body weight patients (BMI > 40 or <15 kg/m2)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study Eadyn alterations induced by intravenous volume expansion and vasopressor infusion in liver transplant recipients.Timepoint: Hemodynamic parameters will be recorded 1) Baseline, 2) Before volume expansion/vasopressor, 3) 5 minutes after volume expansion/vasopressor, | — |
Secondary
| Measure | Time frame |
|---|---|
| To access the potential of baseline Eadyn to anticipate an increase in arterial pressure following volume expansion intra-operatively. Timepoint: Hemodynamic parameters will be recorded 1) Baseline, 2) Before volume expansion/vasopressor, 3) 5 minutes after volume expansion/vasopressor,;To analyse disparity in hemodynamic variables induced by intravenous volume expansion and vasopressor infusion in liver transplant recipients. Timepoint: Hemodynamic parameters will be recorded 1) Baseline, 2) Before volume expansion/vasopressor, 3) 5 minutes after volume expansion/vasopressor,;To confirm the usefulness of Eadyn as a predictor of the arterial pressure response to intravenous fluid administration and vasopressor infusion by simultaneously measuring SVV and PPV.Timepoint: Hemodynamic parameters will be recorded 1) Baseline, 2) Before volume expansion/vasopressor, 3) 5 minutes after volume expansion/vasopressor,;To elucidate the association between baseline Eadyn and rise in arterial pressure induced by intravenous volume expansion and vasopressor infusion. Timepoint: Hemodynamic parameters will be recorded 1) Baseline, 2) Before volume expansion/vasopressor, 3) 5 minutes after volume expansion/vasopressor, | — |
Countries
India
Contacts
Public ContactAnshul Vishnoi
Mahatma Gandhi University of Medical Science & Technology
Outcome results
None listed