Health Condition 1: B- Imaging
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients in surgical intensive care unit who are above 18yrs on mechanical ventilation through endotracheal tube or tracheostomy and eligible for weaning in accordance with the following weaning criteria Signs of reversal of the principal cause of mechanical ventilation Accepted blood oxygenation i.e partial pressure of arterial oxygen (PaO2) equal to more than 60mmHg, partial pressure of arterial carbon dioxide(PaCO2)equal to or less than 45mmHg , fraction of inspired oxygen (FiO2) equal to or less than 0.40, Positive end expiratory pressure (PEEP) equal to or less than 5cmH2O and ratio of partial pressure of arterial oxygen to the fraction of inspired oxygen equal to or more than 200 pH > 7.30; RR index Minimal use of inotropic or vasopressor drugs Stable body hemodynamics Adequate consciousness level Does not receive sedatives or neuromuscular blocking agents Analgesics needed for active pain are continued No fever Absence of hemorrhage or anemia with hemoglobin level > 7.5g/dl No electrolyte disturbances
Exclusion criteria
Exclusion criteria: Patients ï?· Any patient with known neuromuscular disorder ï?· Patients with known congenital lung or pleural malformation ï?· Any patient with post esophageal or thorasic surgeries due to intra operative diaphragmatic manipulation Patients with restrictive lung diseases Super obese patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome was the diagnostic accuracy of diaphragmatic ultrasound parameters for predicting weaning success. Successful weaning from mechanical ventilation was defined as the ability to tolerate spontaneous breathing for at least 48h without any level of assisted ventilation. Weaning failure was defined as the requirement for resumption of either invasive or noninvasive mechanical ventilation or reintubation within 48 hr after extubationTimepoint: 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes are the association between weaning parameters & diaphragmatic dysfunction & reintubation within 48 h after extubation.Timepoint: 48hours | — |
Countries
India
Contacts
RAJAGIRI HOSPITAL