Health Condition 1: R54- Age-related physical debility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 65 years 2.Consent by Patient or Legal Representative 3.Frailty syndrome (>=1 positive out of 5 standardized parameters according to the Physical Frailty Phenotype according to Fried et. al.)
Exclusion criteria
Exclusion criteria: •Severe cardiac or pulmonary disease (NYHA IV, Gold IV) •Intracranial interventions •Moribund patients (palliative situation) •Not enough language skills •Participation in another interventional rehabilitation study or other interventional clinical trial that has not been approved by the study management committee (Exception: Participation in adjuvant intervention study)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Present study will provide the insight into expression profiling of cytokines & chemokines in frail elderly patients. And the impact of Nordic walking will help analyze the alteration in expression profile of the inflammatory proteins. Additionally it will also help in understanding the molecular alterations via plasma derived exosomes. Furthermore study would also help in identifying and explore the potential of the altered molecules as biomarker in frail elderly group.Timepoint: at baseline & at three months | — |
Secondary
| Measure | Time frame |
|---|---|
| not applicableTimepoint: not applicable | — |
Countries
India
Contacts
All India Institute of Medical Sciences