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Impact of Nordic Walking intervention on the characterization of exosomes in frail elderly

Blood plasma derived exosomal profiling of cytokines & chemokines in frail elderly and assessment of impact of Nordic walking intervention on exosomes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053418
Enrollment
200
Registered
2023-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R54- Age-related physical debility

Interventions

Intervention1: Nordic Walking: Consenting Frail patients will be brought to the department of Geriatric Medicine three days in a week to conduct supervised walking on a hard surface, with the Nordi

Sponsors

Indian Council of Medical Research (ICMR)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age >= 65 years 2.Consent by Patient or Legal Representative 3.Frailty syndrome (>=1 positive out of 5 standardized parameters according to the Physical Frailty Phenotype according to Fried et. al.)

Exclusion criteria

Exclusion criteria: •Severe cardiac or pulmonary disease (NYHA IV, Gold IV) •Intracranial interventions •Moribund patients (palliative situation) •Not enough language skills •Participation in another interventional rehabilitation study or other interventional clinical trial that has not been approved by the study management committee (Exception: Participation in adjuvant intervention study)

Design outcomes

Primary

MeasureTime frame
Present study will provide the insight into expression profiling of cytokines & chemokines in frail elderly patients. And the impact of Nordic walking will help analyze the alteration in expression profile of the inflammatory proteins. Additionally it will also help in understanding the molecular alterations via plasma derived exosomes. Furthermore study would also help in identifying and explore the potential of the altered molecules as biomarker in frail elderly group.Timepoint: at baseline & at three months

Secondary

MeasureTime frame
not applicableTimepoint: not applicable

Countries

India

Contacts

Public ContactDr Avinash Chakrawarty

All India Institute of Medical Sciences

pat_avinash@rediffmail.com01126546073

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026