Health Condition 1: - Health Condition 2: D47Z- Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
Conditions
Interventions
Intervention1: Low Dose crossmatched SDAP: Low dose crossmatched SDAP in the same above platelet refractory cases.
Control Intervention1: High dose uncrossmatched SDAP: High dose uncrossmatched SDAP i
Sponsors
PGIMER
Eligibility
Inclusion criteria
Inclusion criteria: • No episode of bleeding at the time of inclusion of patients • Platelet refractory hemato-oncological patients( diagnosis:-aplastic anemia, acute myeloid leukemia, lymphoma, acute lymphoid leukemia, multiple myeloma)with thrombocytopenia having CCI count less than 5,000 at 24 hours post transfusion after two consecutive Single donor Apheresis platelet (SDAP) transfusions
Exclusion criteria
Exclusion criteria: non refractory cases patients having Pyrexia Patients with infection(viral, bacterial and fungal) Patient on drugs causing TCP Bleeding episode DIC Splenomegaly
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To note and compare CCI,PPR after transfusion of SDAP units.Timepoint: 24hors post transfusion. | — |
Secondary
| Measure | Time frame |
|---|---|
| To check bleeding and change in transfusion interval.Timepoint: 24hours post transfusion to 1week. | — |
Countries
India
Contacts
Public ContactSuvetha Rajendran
PGIMER,Chandigarh
Outcome results
None listed