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Link between heart attack and "Clonal Hematopoiesis of Indeterminate Potential" : A Case Control Study

Association between Acute Coronary Syndrome and "Clonal Hematopoiesis of Indeterminate Potential" : A Case Control Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/06/053398
Enrollment
105
Registered
2023-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I219- Acute myocardial infarction, unspecified

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

POST GRADUATE INSTITUE OF MEDICAL EDUCATION AND RESEARCH CHANDIGARH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients with Acute Coronary Syndrome (ST elevation Myocardial Infarction and Non-ST elevation Myoacardial Infarction) presenting to cardiac critical care and emergency will be recruited into the study.

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA: Unwilling to participate in the study Age less than 30 years Haematological or solid organ malignancy Diabetes mellitus duration more than 10 years Smokers Prior history of Coronary Artery Disease Peripheral artery disease Anemia, Hemoglobin Platelets

Design outcomes

Primary

MeasureTime frame
PRIMARY OUTCOMES 1.To compare the odds of having CHIP(Clonal hematopoiesis of Indeterminate Potential) mutations in patients with Acute Coronary Syndrome when compared to healthy population Timepoint: At baseline after diagnosis of Acute Coronary Syndrome

Secondary

MeasureTime frame
SECONDARY OUTCOMES: 1. Echocardiographic and angiographic co-relation in patients who are CHIP(Clonal hematopoiesis of Indeterminate Potential)carriers. 2. Co-relation of pro inflammatory markers such as CRP with CHIP(Clonal hematopoiesis of Indeterminate Potential). Timepoint: At baseline after diagnosis of Acute Coronary Syndrome

Countries

India

Contacts

Public ContactDR RAJESH VIJAYVERGIYA

POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH CHANDIGARH

rajeshvijay999@hotmail.com9419201587

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026