Health Condition 1: J309- Allergic rhinitis, unspecified Health Condition 2: J309- Allergic rhinitis, unspecified
Conditions
Interventions
None listed
Sponsors
Central Council for Research in Ayurvedic Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients either sex ages between 18 to 65 years. 2. IAR or PER (as per the internationally recognized diagnostic standard ARIA), diagnosed by medical history . (Annexure I) 3. Able and willing to participate and provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. History of chronic nasal or upper respiratory tract symptoms or disorders other than allergic rhinitis. 2. History of non allergic rhinitis, chronic sinusitis or serve bronchial asthma. 3. Patients with nasal anatomical defects (grossly deviated nasal septum). 4. Patients with Nasal Polyposis. 5. Patients with associated tonsillitis or airway obstructions (adenoids). 6. Has a nasal condition likely to affect the outcome of the study. 7. Any treatment of H1 antihistamine medication, Non-steroidal analgesics. Corticosteroids Nasal drops, Leukotriene antagonists, Nasal vasoconstrictors. 8. Patients with a history of surgical procedure on the nose like Septoplasty/Submucous resection, Inferior turbinate reduction, Endoscopic sinus surgery. 9. Pregnant ladies and Lactating mothers. 10. Patients suffering from any debilitating chronic disease like tuberculosis, Uncontrolled Diabetes mellitus 11. Any unstable cardio-vascular diseases 12. Patients with evidence of malignancy. 13. Patients with concurrent hepatic disorder (defined as Aspartate Amino Transferase (AST) and / or Alanine Amino Transferase (ALT) > 2 times upper normal limit or Renal Disorders (defined as S. creatinine > upper limit of Lab. value), Pulmonary Dysfunction (Bronchial Asthma and / or Chronic Obstructive Pulmonary Disease [COPD]) 14. Patient has an acute mental disorder 15. Patients who are currently participating in any other clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oMean change in the CARAT (Control of Allergic Rhinitis and Asthma Test) ScoreTimepoint: On base line, 16th day, 31st day, 45th day, 75th day, 105th day, 135th day | — |
Secondary
| Measure | Time frame |
|---|---|
| o Mean change in the Nasal Endoscopy Index (assessment of nasal membrane color (pale or hyperemia), rhinorrhea (watery or yellow), and inferior turbinate swelling (hypertrophy). o Mean change in the Laboratory investigations Timepoint: On baseline and 45th day | — |
Countries
India
Contacts
Public ContactDr Shivshankar Rajput
Safadarjung Hospital Delhi
Outcome results
None listed