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BENEFITS OF TOPICAL INSULIN IN MAXILLOFACIAL WOUND HEALING.

EFFECTS OF TOPICAL INSULIN ON MAXILLOFACIAL WOUNDS: A DOUBLE-BLIND RANDOMISED CONTROL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/06/053384
Enrollment
46
Registered
2023-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S014- Open wound of cheek and temporomandibular area

Interventions

Intervention1: Collection of blood samples and tissue sample: Tissue sample 0.03-0.05g in weight will be collected from the cleanest area of wound in PBS medium and Trizol reagent is added. [Tissue sa

Sponsors

Dr Jyoti Mishra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients reporting to the casualty/Dept with maxillofacial soft tissue wounds within 48 hours. Abrasion greater than or equal to 3x3 cm and less than or equal to 6x6 cm. Patients of any gender above 18 years of age and willing to take part in the trial. Patients admitted or willing for everyday follow-up.

Exclusion criteria

Exclusion criteria: Patients having infected wounds(As determined by the presence of visible pus, from the wound) and any previous intervention done. Patients who have suffered burns- any degree. Wounds requiring suturing will be excluded. Patient not willing to give informed consent. Patients with debilitating systemic conditions(Except well controlled diabetic patients not on systemic insulin), syndromic patients and patient with psychological disorders. Pregnant/Lactating women

Design outcomes

Primary

MeasureTime frame
The insulin treated wounds show accelerated healing as compared to 0.9% Normal salineTimepoint: Wounds treated with insulin heals in around 05 days

Secondary

MeasureTime frame
There is no significant effect of Topical Insulin on wound healing when compared to 0.9% Normal SalineTimepoint: Wounds treated with either Topical Insulin or Normal Saline take 7-10 days to heal

Countries

India

Contacts

Public ContactDr Jyoti Mishra

AB Shetty Memorial Institute of Dental Sciences

draravindkarikal@nitte.edu.in9008964130

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026