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Do patients with Hepatopulmonary syndrome undergoing liver transplant need a longer time on ventilator?

Post-operative mechanical ventilation and outcome in patients with Hepatopulmonary syndrome undergoing Orthotopic living donor liver transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/06/053370
Enrollment
50
Registered
2023-06-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K720- Acute and subacute hepatic failure Health Condition 2: K703- Alcoholic cirrhosis of liver Health Condition 3: K721- Chronic hepatic failure Health Condition 4: C220- Liver cell carcinoma Health Condition 5: K746- Other and unspecified cirrhosis ofliver Health Condition 6: K766- Portal hypertension

Interventions

None listed

Sponsors

Institute of Liver and Biliary Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -All the patients that underwent living donor liver transplantation at the Institute of Liver and Biliary Sciences - The patients that meet the criteria for hepatopulmonary syndrome (HPS) diagnosis I.e. 1) A-a O2 gradient >15mmHg 2) Intrapulmonary shunting shown by agitated Saline Contrast Echocardiography in the presence of severe hepatic function impairment (Child-Pugh class B/C)

Exclusion criteria

Exclusion criteria: Patients whose complete data is not available

Design outcomes

Primary

MeasureTime frame
To identify the predictors of prolonged mechanical ventilation (more than 48hrs; PPMV) in patients with Hepatopulmonary syndrome (HPS) undergoing Orthotopic Living donor liver transplantation (LDLT)Timepoint: Post LDLT—

Secondary

MeasureTime frame
To identify the predictors of poor outcome at 1-month post transplant in patients with Hepatopulmonary syndrome (HPS) undergoing Orthotopic Living donor liver transplantation (LDLT)Timepoint: 1 month Post LDLT—

Countries

India

Contacts

Public ContactDr Gaurav Sindwani

Institute of Liver and Biliary Sciences

drsindwani25@gmail.com8728089898

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026