Health Condition 1: Q20-Q28- Congenital malformations of the circulatory system Health Condition 2: I00-I99- Diseases of the circulatory system
Conditions
Interventions
Intervention1: Sugammadex: Reversal with 2 mg/kg dose of Sugammadex after the completion of procedure and after two twitches on Train Of Four.
Control Intervention1: Neostigmine: Reversal with 0.05 mg
Sponsors
Institutional Research Society
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I-IV patients. 2. Age between 20 and 60 years. 3. Patients posted for elective cardiac catheterisation procedures in the cathlab. 4. Availability of informed consent and willingness of the patient to be a part of the study.
Exclusion criteria
Exclusion criteria: 1. Patients requiring emergency surgery. 2. Incapacity to consent 3. Patient with renal, hepatic and pre-existing pulmonary comorbidities. 4. Patients allergic to Sugammadex, neostigmine or glycopyrrolate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our primary outcome is to note the time(in minutes) from re-appearance of second twitch to TOF ratio more than 0.9 with sugammadex compared to neostigmine groups. This is a parameter to measure the efficacy of the study drugs.Timepoint: Baseline, Just before extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 2) To measure the time to PACU discharge readiness using the modified Aldrete score in both the study groups.Timepoint: two hours after shifting to icu, four hours after shifting to icu, six hours after shifting to icu, eights hours after shifting to icu;to detect the occurrence of any adverse events after administration of study drugTimepoint: 2 hours, 4 hours, 6 hours, 8 hours | — |
Countries
India
Contacts
Public ContactSanjeeta Umbarkar
Seth GS Medical College and KEM Hospital
Outcome results
None listed