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Research on Acanthosis Nigricans (Jild ka kalapan/ Mailapan) in Unani System of Medicine

Efficacy of Joshanda Haleela Siyah orally with Zimad of Samandar Jhaag and Badam Talkh Muqasshar in Acanthosis Nigricans- A Randomized Single Blind Placebo Controlled Clinical Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/053339
Enrollment
40
Registered
2023-05-31
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L83- Acanthosis nigricans

Interventions

Intervention1: Oral:Joshanda Haleela Siyah Topical: Zimad of Samandar Jhaag and Badam Talkh Muqasshar: In the patients of group A, Joshanda Haleela Siyah is given for oral administration on empty stom

Sponsors

National Institute of Unani Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Clinically diagnosed cases of acanthosis nigricans on neck. 2.Patients between the age of 18-50 years 3.All genders. 4.Known cases of Serum Insulin Resistance, Metabolic Syndrome and PCOD. 5.Patients who will give consent and able to do follow up.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women. 2.Patients having acanthosis >5 years. 3.Patients who previously applied topical treatments like retinoid, hydroquinone, or corticosteroid or any depigmenting agents or any cosmetic procedure within 1 month prior to study. 4.Patients who took following medications like contraception pill, nicotinic acid, steroid, estrogen, niacin, protease inhibitors, within 1 month of study. 5.Types of acanthosis other than benign and endocrine type. 6.K/H/O malignancy

Design outcomes

Primary

MeasureTime frame
1.Decrease in Burke Scale 2.Change in color indices of Felix Von Luschan Color chartTimepoint: 30 Days

Secondary

MeasureTime frame
1.Investigator assessment using Photography. 2.DermoscopyTimepoint: 30 Days

Countries

India

Contacts

Public ContactProf Mohd Aleemuddin Quamri

National Institute of Unani Medicine

sarimnium@gmail.com7767993333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026