A clinical trial to compare the efficacy of Varmam manipulation with & without of Punginpattai kashayam(internal) Mukkootu ennai I (external)in the management of Korai Vatham (Lumbar spondylosis with radiculopathy).

An open labelled double arm non randomized phase II clinical trial,To compare the efficacy of Varmam manipulation with & without of Punginpattai kashayam(internal) Mukkootu ennai I(external) in the management of Korai Vatham.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/053296

Enrollment

Registered

2023-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M472- Other spondylosis with radiculopathy

Interventions

Intervention1: Varmam manipulation: External stimulation of Varma points by firm pressure (twice a week) for 48 days Control Intervention1: Varmam manipulation along with Punginpattai kashayam(interna

Eligibility

Inclusion criteria

Inclusion criteria: Patients having symptoms of pain in the lumbar region,Radiating pain to buttocks and lower limb,stiffness present in lumbar region Exacerbation of pain on movements,pain increased on forward bending,tingling sensation and numbness Patients who are willing to give radiological investigation and provide blood for lab investigation Patients who are willing for admission and stay IPD or willing to attend OPD patient willing to sign informed consent document

Exclusion criteria

Exclusion criteria: Congenital anomalies Autoimmmune diseases Inflammatory arthritis associated with HLA B27 Scheuermanns disease Paget disease of bone Infectious diseases Inflammatory bowel diseases Osteoporotic fracture Traumatic fracture Diabetes mellitus Neoplasia Cardiac diseases Liver diseases Renal diseases Pregnant women and lactating mother Patient with any other serious illness

Design outcomes

Primary

Measure	Time frame
Outcome of the clinical trial is mainly assessed by reduction in the clinical symptoms by following assessments Femoral nerve stretch test Straight leg raise test Oswestry Low back disability index Functional strength of lumbar spine Comparision of change from baseline in Oswestry Low back Disability Index at day 48 between group I & group II Study will reveal the effectiveness of Varmam manipulation & the trial drug for the management of Korai Vatham (Lumbar spondylosis with radiculopathy)Timepoint: 48 days	—

Measure

Time frame

Outcome of the clinical trial is mainly assessed by reduction in the clinical symptoms by following assessments Femoral nerve stretch test Straight leg raise test Oswestry Low back disability index Functional strength of lumbar spine Comparision of change from baseline in Oswestry Low back Disability Index at day 48 between group I & group II Study will reveal the effectiveness of Varmam manipulation & the trial drug for the management of Korai Vatham (Lumbar spondylosis with radiculopathy)Timepoint: 48 days

—

Secondary

Measure	Time frame
Secondary outcome of the trial will assess the safety profile of the trial drug, pharmacological and biochemical activity of the trial drug.Timepoint: 48 days	—

Countries

India

Contacts

Public ContactDr A Muneeswaran

Government siddha medical College and hospital

sujatharajasekar66@gmail.com9442331462

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026