Health Condition 1: C700- Malignant neoplasm of cerebral meninges
Conditions
Interventions
Intervention1: To assess and compare effect o intravenous tranexamic acid on blood loss in adult patients undergoing excision of intracranial meningioma and normal saline:
Tranexamic acid will be giv
Sponsors
Vardhman Mahavir Medical College and Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: American society of anaesthesiologist physical status classification sysytem grade 1 and 2 undergoing elective excision of intracranial meningioma with radiographic finding of diamteter more than 5cm in atleast two dimensions.
Exclusion criteria
Exclusion criteria: Deranged liver/renal function test, pre operative anaemia, history of allergy to tranexamic acid, pregnancy and history of significant thromboembolic episodes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare the difference in blood loss in intracranial meningioma excisionTimepoint: To assess and compare the difference in blood loss in intracranial meningioma excision during the surgery and within next 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| need of blood transfusion and change in fibrinogen levels.Timepoint: total blood products transfused intra operatively and post operatively assessment of serum fibrinogen levels pre operatively and two hours after loading dose. | — |
Countries
India
Contacts
Public ContactAKSHAY YADAV
vardhman mahavir medical college and safdarjung hospital
Outcome results
None listed