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Time toxicity in patients receiving palliative chemotherapy

“Observational study on the ‘Toxicity of time’ in patients with advanced cancer receiving palliative chemotherapy ?

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/05/053281
Enrollment
109
Registered
2023-05-31
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

None listed

Sponsors

Sharada Mailankody
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with advanced stomach, pancreaticobiliary, hepatocellular carcinoma 2. Patients with carcinoma colon on third-line chemotherapy 3. Patients with grade 4 glioma on second-line therapy 4. Patients with head and neck squamous cell carcinoma on second line therapy 5. Patients with carcinoma lung on third line chemotherapy 6. Patients with platinum refractory carcinoma ovary after 2 lines of chemotherapy 7. Patients with carcinoma cervix on second line chemotherapy 8. Germ cell tumors after third line chemotherapy

Exclusion criteria

Exclusion criteria: 1. Patients already on palliative IV chemotherapy for more than two months 2. Patients with altered sensorium, psychiatric issues, who may not comprehend the questions in the questionnaire 3. Patients with Eastern Cooperative Oncology Group performance status (ECOG PS) >2 4. Terminally ill patients who are planned only for best supportive care 5. Pediatric patients

Design outcomes

Primary

MeasureTime frame
Time toxicity ratioTimepoint: 30 days

Secondary

MeasureTime frame
- Relate time toxicity with overall survival - Relate time toxicity with quality of life with the EuroQoL-5 questionnaire. Timepoint: 30 days

Countries

India

Contacts

Public ContactSharada Mailankody

Kasturba Medical College, Manipal

sharadajayaram27@gmail.com08202922779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026