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post operative pain after non surgical treatment of open apex maxillary central incisors

Effect of PRF and MTA apical barrier Non-Surgical Root Canal Treatment on Post-operative Pain : A Randomized Clinical Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/053223
Enrollment
35
Registered
2023-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: PRF: The obtained PRF will cut into small fragments using scalpel blade and will placed incrementally inside the canal using suitable endodontic pluggers till the level of the cemento-e

Sponsors

Dr. Umesh Kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects will be free from any chronic systemic disease, both gender with age range from 15 to 40 years, tooth in question is restorable, permanent necrotic maxillary incisors with incomplete root development without periapical lesions, pulp involvement is either due to caries or trauma and selected teeth have never been subjected to any line of endodontic treatment.

Exclusion criteria

Exclusion criteria: patient show allergic response to ciprofloxacin, metronidazole or minocycline or against any materials which we will use in the study, grossly decayed or fractured teeth that required post and core as final restorations, presence of draining sinus and presence of periodontal pockets, Radiographically, apical foramen less than 1 mm, presence of periapical radiolucency more than 10 mm, presence of external or internal root resorption as well as patients with a history of major surgeries like cardiac, kidney transplantation, haemodialysis, radiographic or clinical identification of ankylosis, root resorption, root fracture, uncooperative patients and legal guardians will not consent to participate in the study.

Design outcomes

Primary

MeasureTime frame
the incidence and intensity of post-operative pain on VAS with PRF scaffolds, MTA as apical barrier in immature maxillary permanent incisors with necrotic pulp.Timepoint: the incidence and intensity of post-operative pain on VAS with PRF scaffolds, MTA as apical barrier in immature maxillary permanent incisors with necrotic pulp by subjects after 24 hours, 48 hours and 72 hours post operatively.

Secondary

MeasureTime frame
To record the frequency of analgesic intakeTimepoint: by subjects after 24 hours, 48 hours and 72 hours post operatively.

Countries

India

Contacts

Public ContactUMESH KUMAR

post graduate institute of medical education and research

odharmani911@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026