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To compare two doses of intravenous Dexmedetomidine in alleviating pain on propofol injection in patients undergoing elective surgery under general anaesthesia and to assess pain score

Comparative evaluation of two doses of intravenous dexmedetomidine in alleviating pain on propofol injection in patients undergoing elective surgery under general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/053174
Enrollment
70
Registered
2023-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: An intravenous single dose of dexmedetomidine 0.6mcgkg-1 diluted with isotonic saline to a volume of 10ml to be given over 10 minutes.: An intravenous single dose of dexmedetomidine 0

Sponsors

Pt. B.D. Sharma PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to American society of Anaesthesiology grade I and II 2. Age between 18-60 years 3. Either sex 4. Patients posted for elective surgery under general anaesthesia of duration 1-3hrs

Exclusion criteria

Exclusion criteria: 1.Patients with obesity (BMI >55kgm-2) 2.Patients with history of allergy to test drug 3.Patients with history of hepatic and renal dysfunction 4.Patients with history of psychological disorders 5.Patients with history of alcohol and drug abuse 6.Patients with Heart rate 7.Refusal to participate in the study

Design outcomes

Primary

MeasureTime frame
To compare and study the effectiveness of two doses of intravenous dexmedetomidine in alleviating pain on propofol injection. To note down changes in HR and MAP.Timepoint: Assessment of patients’ motor and verbal reactions, from time of propofol injection to loss of consciousness. HR and MAP will be noted : 1.Immediately before injection of study drug 2.pre-induction 3.post-induction 4.pre-intubation 5.post-intubation.—

Secondary

MeasureTime frame
To note the side effects of intravenous dexmedetomidine if any.Timepoint: To note the side effects of intravenous dexmedetomidine if any during the induction and intraoperatively—

Countries

India

Contacts

Public ContactDr Chaitali Pandey

Pt. B.D. Sharma PGIMS, Rohtak

kadnandita@gmail.com9896335544

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026