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IN ESOPHAGUS CANCER PATEINTS TO VALIDATE NEW INTERPRETATION FINDINGS ON EARLY FDG PET-CT SCAN, AFTER PRE OPERATIVE CHEMO-RADIATION WITH AFTER OPERATION HISTOPATHOLOGY FINDINGS .

TO ESTABLISH NEW INTERPRETATION CRITERIA ON EARLY FDG PET-CT SCAN, POST NEOADJUVANT CHEMO-RADIATION WITH POST OPERATIVE HISTOPATHOLOGY IN PATIENTS WITH CARCINOMA ESOPHAGUS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/05/053168
Enrollment
20
Registered
2023-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C159- Malignant neoplasm of esophagus, unspecified

Interventions

None listed

Sponsors

AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: I. Age more than or equal to 18 years. II. Histologically proven esophageal cancer patients III. Patients who are planned for nCRT followed by esophagectomy with curative intent. IV. Patients with carcinoma esophagus who have undergone FDG PET-CT for both staging and post 4-7 weeks of nCRT.

Exclusion criteria

Exclusion criteria: I. Patients with known carcinoma esophagus and distant metastases. II. Patients who did not undergo esophagectomy for various reasons (lost to follow up, death, complications of nCRT, co-morbidities or disease progression). III. Pregnant and breastfeeding women. IV. Non-compliant patients.

Design outcomes

Primary

MeasureTime frame
To determine the diagnostic accuracy of new interpretation criteria to categorize inflammatory changes and residual tumor on early FDG PET-CT within 4-7 weeks of nCRT in esophageal cancer patients with post operative histopathology as gold standard.Timepoint: After completion of scans AT BASELINE AND AFTER 4-7 WEEKS OF CTRT COMPLETION—

Secondary

MeasureTime frame
1. To compare new FDG PET-CT criteria with the existing PERCIST 1.0 to predict residual disease post nCRT in patients with carcinoma esophagus.Timepoint: After completion of scans AT BASELINE AND 4-7 WEEKS AFTER CTRT COMPLETION;2. To analyse semiquantitative metabolic parameters on early FDG PET-CT corresponding to radiation induced inflammation in post-surgery histopathology examination for carcinoma esophagus.Timepoint: After completion of scans AT BASELINE AND 4-7 WEEKS AFTER CTRT COMPLETION—

Countries

India

Contacts

Public ContactDr Sameer K Taywade

AIIMS Jodhpur

sameertaywade@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026