Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Treatment I: Cisatracurium
0.15 mg/kg IV
single loading dose, time taken for the onset of action is noted using neuromuscular train of four(TOF) monitors.
Body weight according to ide
Sponsors
Department of Anaesthesia
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients posted for elective surgery under general anesthesia. 2.ASA II and III patients 3.BMI greater than 30
Exclusion criteria
Exclusion criteria: 1.Known allergy to cisatracurium or benzene sulphonic acid. 2.Pregnant patients 3.Patients with history of any neuromuscular disease 4.Patients undergoing treatment with medication known to interfere with neuromuscular transmission. 5.Deranged renal or hepatic function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Onset of action of cisatracurium - defined as time taken from administration of intubating bolus dose till the TOF count to reach zero. 2.Duration of action of bolus dose of cisatracurium â?? defined as time taken for TOF to reach â?¥2 from 0Timepoint: 1. a)baseline b)time at which TOF count becomes zero 2. a)time at which TOF count becomes zero b)time at which TOF count becomes more than or equal to 2 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.supplemntary doses required 2.surgical field conditionsTimepoint: 1.baseline 2.at the start of surgery | — |
Countries
India
Contacts
Public ContactPrajith Bhaskaran
Guru Gobind Singh Indraprastha University, Delhi
Outcome results
None listed