Health Condition 1: D699- Hemorrhagic condition, unspecified
Conditions
Interventions
None listed
Sponsors
INDIRA GANDHI INSTITUTE OF CHILD HEALTH
Eligibility
Inclusion criteria
Inclusion criteria: All Neonates with gestational age of >28weeks,within 14 days of life. Should have received birth dose of vitamin-k. Received antibiotics for 7 days . Informed parental consent Willing for follow up till 4 weeks of age.
Exclusion criteria
Exclusion criteria: Neonates with major congenital malformations or life threatening diseases. Neonatal cholestasis or any other medical conditions causing vitamin-k deficiency. Neonates on prolonged TPN, cholestasis etc receiving prophylactic vitamin-k. Neonates receiving vitamin-k antagonists. Neonates born to mother who have received or currently receiving vitamin-k antagonists ,anticonvulsants or anti-TB drugs. Neonates receiving anticonvulsants or anti-TB. Neonates with acute kidney injury (serum creatinine >1.5mg/dl).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the proportion of neonates with biochemical vitamin-k deficiency after 7 days of antibiotic therapyTimepoint: To evaluate the proportion of neonates with biochemical vitamin-k deficiency after 7 days of antibiotic therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the proportion of neonates with biochemical vitamin-k deficiency after 4 weeks of last antibiotic dose. To evaluate the proportion of neonates with late HDN or clinically significant bleeding. Timepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactDr JAGATH
INDIRA GANDHI INSTITUTE OF CHILD HEALTH
Outcome results
None listed