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Effective local anaesthetic volume to provide surgical anaesthesia for parasacral sciatic nerve block.

Median effective local anaesthetic volume for ultrasound guided parasacral sciatic nerve blockade: A prospective dose finding study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/053126
Enrollment
55
Registered
2023-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Parasacral sciatic nerve block using 0.5% ropivacaine: Dose-Volume of drug will be determined using Dixons up down method(based on response to block in previous patient) Concentration -

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between age group 18-80 years undergoing traumatic below knee orthopaedic surgery ASA physical status I-III of both sex

Exclusion criteria

Exclusion criteria: a) Patient refusal b) Allergy to local anaesthetic drugs c) Chronic opioid therapy d) Thrombocytopenia/coagulopathy, e) Anti-coagulant and thrombolytic therapy f) Morbid obesity (BMI >35 with obesity symptoms or BMI > 40) g) Neurological diseases h) Infections in the intervention site i) Patients with psychiatric illness

Design outcomes

Primary

MeasureTime frame
Median effective volume of 0.5% ropivacaine for a successful ultrasound guided parasacral sciatic nerve block for surgical anaesthesia in 50% patients (ED50).Timepoint: 20 mins—

Secondary

MeasureTime frame
Volume of 0.5% ropivacaine for surgical anaesthesia in 95% patients (ED95).Timepoint: 20 mins—

Countries

India

Contacts

Public ContactDr Tanvir Samra

Post Graduate Institute Of Medical Education and Research, Chandigarh

drtanvirsamra@yahoo.co.in7087262379

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026