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autologous platelet rich plasma for Ovarian rejuvenation

Effect of autologous platelet rich plasma in Ovarian rejuvenation in infertile female with poor ovarian reserve: an open label randomised controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/053123
Enrollment
60
Registered
2023-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N978- Female infertility of other origin

Interventions

Intervention1: Intraovarian injection of autologous Platelet rich plasma.: Autologous Platelet rich plasma intra ovarian injection will be given between day 7 and day 9 of periods for three consecutiv

Sponsors

VMMC and Safdarjung hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Serum AMH (Anti Mullerian Hormone) AFC (Antral Follicle Count) Serum FSH(Follicle Stimulating Hormone) > 12, Hb >11 gm% and platelets >1.5 lakhs.

Exclusion criteria

Exclusion criteria: previous history of Pelvic Inflammatory Disease (PID), Suspected pelvic adhesions, known clinical/biochemical hyperandrogenism or PCOS, Severe male factor infertility, history of symptoms of platelet dysfunction such as easy bruisability, frequent nose-bleeds, heavy menstrual bleeding, bleeding gums or excessive bleeding during dental procedures ,blood borne disease like Hepatitis B, Hepatitis C, Syphilis, HIV, NSAIDs intake in 10 days before the procedure ,patient on anticoagulant therapy, mullerian abnormality, Ashermann Syndrome, moderate /severe endometriosis, active vaginal/cervix infection, any significant co-morbidity/ psychiatric disorder which compromise or interfere with consent giving/study participation/ follow up or interpretation of study.

Design outcomes

Primary

MeasureTime frame
1.Antral Follicle Count (defined as all follicles of 2-9 mm on day 2 scan on TVS), 2.Serum AMH 3.Serum FSH at the end of the treatment cycle. Timepoint: 3 months

Secondary

MeasureTime frame
conception rateTimepoint: after 3 months

Countries

India

Contacts

Public Contactdr Divya Pandey

Vardhman Mahavir Medical College and Safdarjung Hospital

dr_devya1@yahoo.co.in8860198440

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026