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clinical trial to compare two different drugs, midazolam and dexmedetomidine to reduce high blood pressure in patients undergoing cataract surgery

comparative study of effects of low dose midazolam and low dose dexmedetomidine on hemodynamics and surgical comditions in hypertensive patients undergoing cataract surgery under local anaesthesia- a prospective comparative study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/053071
Enrollment
80
Registered
2023-05-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Midazolam: Midazolam 20mcg per kg intravenous route one dose to reduce blood pressure Control Intervention1: midazolam and dexmedetomidine: low dose midazolam and dexmedetomidine for re

Sponsors

Dr Ashwini H
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA1 &ASA2 patients undergoing cataract surgery under local anaesthseia with preop blood pressure more than 140/90 mmHg

Exclusion criteria

Exclusion criteria: patients on beta blockers patients with hard of hearing mentally retarded patients patients with known allergy to study drugs

Design outcomes

Primary

MeasureTime frame
Efficacy of study drugs on lowering the blood pressureTimepoint: Outcome will be assessed at baseline every 5 min till the end of the surgery—

Secondary

MeasureTime frame
delay in discharge from hospitalTimepoint: after surgery;effect of study drugs on other vitalsTimepoint: intraoperatively;movement during injectionTimepoint: during intraocular block;sedation scoreTimepoint: intraoperatively—

Countries

India

Contacts

Public ContactDr Ashwini H

Rajarajeshwari medical medical college

drashwinih@rediffmail.com8971265579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026