Health Condition 1: J329- Chronic sinusitis, unspecified Health Condition 2: J339- Nasal polyp, unspecified
Conditions
Interventions
Intervention1: Melatonin 5 mg: Melatonin 5 mg given orally Once 90 minutes before the proposed surgical procedure
Control Intervention1: Placebo (similar looking pill): Placebo administered Once 90 mi
Sponsors
MS Ramaiah Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Age 20-65 years Patients undergoing nasal surgeries under general anaesthesia and requiring nasal packing after surgery
Exclusion criteria
Exclusion criteria: BMI greater than or equal to 30 kg/m2 Uncontrolled hypertension or diabetes mellitus Uncontrolled asthma or COPD Ischemic heart disease or other cardiac disorders Kidney or liver diseases Cognitive impairment Chronic use of antipsychotic medications or substance use disorder Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Emergence Agitation as assessed by Ricker sedation agitation scaleTimepoint: Emergence Agitation will be assessed 2 minutes after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation as assessed by Modified Ramsay sedation scaleTimepoint: 5 minutes before administering general anaesthesia;Time to verbal responseTimepoint: Time in minutes for patient to respond to verbal commands after discontnuation of anaesthetics will be noted (as soon as patient opens his/her eyes to verbal request) | — |
Countries
India
Contacts
Public ContactDr Tejesh C A
MS Ramaiah Medical College
Outcome results
None listed