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Comparison of Ram cannula and short binasal prongs in delivering CPAP

Comparison of Ram cannula and short binasal prongs in delivering CPAP on targeting mean oropharyngeal pressures - A randomised non-inferiority trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052972
Enrollment
98
Registered
2023-05-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J988- Other specified respiratory disorders

Interventions

Intervention1: Ram cannula targeting mean oropharyngeal pressures: Baby will be provided CPAP with Ram cannula targeting mean oropharyngeal pressures and pressures will be measured at 0,12,24 hours of

Sponsors

Richa Singh Rajawat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Any neonate 28-<=35 weeks gestation requiring NICU admission for respiratory distress within 6 hours of life (28-<=32 weeks & 32-<=35weeks), Fio2 requirement <40%

Exclusion criteria

Exclusion criteria: Major congenital malformation Birth asphyxi Encephalopathy Shock Need for intubation in first 6 hours of life Poor spontaneous respiratory efforts Denial of consent

Design outcomes

Secondary

MeasureTime frame
1. CPAP failure (Need for change of interface / escalation of respiratory support within 72 hours of randomization) 2. Nasal trauma 3. All-cause mortality till discharge 4. Surfactant requirement 5. Air leaks 6. NEC 7. ROP requiring treatment 8. Duration of NICU stay 9. Duration of hospital stay Timepoint: At end of 72 hours

Primary

MeasureTime frame
To compare the efficacy in Ram cannula and short binasal prongs group by assessing duration of CPAP in preterm neonates (28-â?¤35 weeks) with respiratory distress managed on bubble CPAP as primary respiratory support targeting the mean delivered oropharyngeal pressures.Timepoint: Mean oropharyngeal pressures will be measured at 0, 12, 24 hours of starting CPAP support

Countries

India

Contacts

Public ContactMangala bharathi

Madras medical College

drmangalabharathi@gmail.com9840786836

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026