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analysis of flow in kidney blood vessels to predict kidney injury earlier, in adult living donor liver transplant patients

Renal Resistive index as a predictor of acute kidney injury in patients undergoing living donor liver transplantation – a prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/05/052918
Enrollment
100
Registered
2023-05-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K769- Liver disease, unspecified Health Condition 2: O- Medical and Surgical

Interventions

None listed

Sponsors

Dr Rela Institute and Medical Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. To assess whether RRI could predict acute kidney injury in the post-operative period in patients undergoing living donor liver transplantation

Exclusion criteria

Exclusion criteria: 1. To find the correlation between trough tacrolimus levels and RRI. 2. To find the association between urea, creatinine, estimated glomerular filtration rate and RRI. 3. To assess whether RRI could predict recovery from acute kidney injury. 4. To assess the changes in RRI and its association with patient outcomes – sepsis, mechanical ventilation, wound infection, length of ICU stay and hospital stay.

Design outcomes

Primary

MeasureTime frame
increase in RRI will preceede the changes in creatinine and will help to predict AKI earlyTimepoint: Pre operative day, POST OPERATIVE 01 TO POST OPERATIVE 05—

Secondary

MeasureTime frame
Association between RRI & Tacrolimus trough levels Association of RRI with blood Urea,s.creat, eGFR Whether could predict recovery from AKI Timepoint: POST OPERATIVE day 01 to post OPERATIVE day 05—

Countries

India

Contacts

Public ContactDr Amal Francis Sam

Dr Rela Institute and Medical Centre

amalfsam@gmail.com8968163281

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026