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Comparison of use of two types of pain medicines in extraction of teeth

Comparative Evaluation of Pre-Emptive and Post-Operative Analgesic Effectiveness of Ibuprofen versus Ketorolac in Intra-alveolar Extraction of Teeth ââ?¬â?? A Prospective, Randomized, Double- Blind Clinical Study.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052842
Enrollment
128
Registered
2023-05-18
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K02- Dental caries Health Condition 2: K04- Diseases of pulp and periapical tissues Health Condition 3: K05- Gingivitis and periodontal diseases Health Condition 4: K083- Retained dental root

Interventions

Intervention1: Ibuprofen group A1: Pre-emptive analgesic group recieving tablet Ibuprofen 400mg 8 hourly started 24 hours prior to extraction and continued for three days post extraction Interve

Sponsors

MGM Dental College and hospital Navi Mumbai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients indicated for simple intra-alveolar dental extraction. 2) Both males and females. 3) Patients in 18 to 60 years of age. 4) Patients fulfilling ASA 1 and ASA 2 Fitness for Dental extraction. 5) Patients participating in the study voluntarily.

Exclusion criteria

Exclusion criteria: 1) Patients with Acute pain and Space infections requiring immediate care. 2) Patient already taking analgesics for other conditions. 3) Patients requiring extraction of more than two adjacent teeth 4) Teeth requiring surgical extractions. 5) Patients Allergic to Local anesthetic solution and its contents. 6) Patients allergic to Ibuprofen and Ketorolac. 7) Pregnant patient requiring Dental extraction.

Design outcomes

Primary

MeasureTime frame
To compare the preemptive analgesic efficacy of Ibuprofen and Ketorolac in Intra-alveolar Extraction of teeth.Timepoint: 24 hours preoperatively and 3 days postoperatively

Secondary

MeasureTime frame
To compare the analgesic efficacy of Ibuprofen and Ketorolac prescribed within an hour post extraction before the Local anesthetic effect subsides.Timepoint: 3 days postoperatively;To analyze the best prescription regimen for Ibuprofen and Ketorolac amongst Preemptive and Postoperative prescription for Dental Extraction.Timepoint: 24 hours preoperatively and 3 days postoperatively

Countries

India

Contacts

Public ContactDhrishi Patel

MGM Dental College and hospital Navi Mumbai

drpadmakar22@gmail.com7506183692

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 27, 2026