Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sevoflurane, I.v. Mephentermine, I.v. Atropine and I.v. Esmolol: Hypertensive episodes are treated by adjusting dial concentration of inhalational agent sevoflurane. Hypotensive episode
Sponsors
M REETHM
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing elective surgery under general anesthesia and with valid consent 2.ASA grade 1 and 2 patients
Exclusion criteria
Exclusion criteria: 1.Emergency surgeries 2.Prior sensitization or allergic reaction to propofol, ketamine, soy or egg products hemodynamic instability 3.Head injury 4.Increased intracranial or intraocular pressure 5.Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamic stability in terms of systolic blood pressure, diastolic blood pressure and mean arterial pressure are maintained when patient is induced with ketofol (combination of propofol and ketamine ) rather than when used alone as an induction agentsTimepoint: Baseline , 1 minute ,3minutes , 5 minutes ,15 minutes after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease in post operative nausea and vomiting and decreased incidence of hallucinationsTimepoint: Immediately after extubation, 15 minutes , 30 minutes and 1 hour after extubation | — |
Countries
India
Contacts
Public ContactM REETHM
NIZAMS INSTITUTE OF MEDICAL SCIENCES
Outcome results
None listed