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To compare the efficacy of fluperitien malleate and ibuprofen in reducing post operative pain trismus and swelling

To compare the efficacy of Flupirtine maleate and ibuprofen in reducing post operative complications related to third molar surgery _ A double blinded randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052832
Enrollment
96
Registered
2023-05-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: FLUPIRTINE MALEATE: DOSE : 100 MG TDS for 3 days Intervention2: IBUPROFEN 400 mg TDS : IBUPROFEN 400 mg TDS for 3 days

Sponsors

DR pAswini
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I patients 1) In the age group 18 to 40 and of either gender. 2) CLASS I,II AND POSITION A,B impacted 3rd molar (according to PELL and GREGORY classification ). 3)Patient who is willing to participate in study

Exclusion criteria

Exclusion criteria: ASA II,III,IV patient . 1) CLASS III AND POSITION C impacted 3rd molar (according to PELL and GREGORY classification ) 2) Acute infection 3) Patient allergic to flupirtine maleate and Ibuprofen 4) Patient having gastric ulcer 5) Patient on analgesics for past 1 week . 6) Patient with systemic disease, pregnancy and lactating women or any other medical therapy that could interfere with healing process . 7) Immunocompromised patient 8) Mentally challenged patient. 9) Patient who is not willing to participate in study.

Design outcomes

Primary

MeasureTime frame
pain swelling trismusTimepoint: 1st post op day 3rd post op day 7th post op day 12th post op day

Secondary

MeasureTime frame
git symptomsTimepoint: 1st post op day 3rd post op day 7th post op day 12th post op day

Countries

India

Contacts

Public ContactDr P Aswini

SRI Venkateshwaraa Dental College

omfssvdc@gmail.com6385813272

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026