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Dengue Severity in Children: Detecting Warning Signs through Proteinuria and Gall Bladder Health

Proteinuria and gall bladder wall thickness as predictive indicators of dengue severity in pediatric patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/05/052808
Enrollment
74
Registered
2023-05-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A90- Dengue fever [classical dengue]

Interventions

None listed

Sponsors

University College of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Probable dengue and confirmed dengue as per WHO 2020 guidelines

Exclusion criteria

Exclusion criteria: 1.Patients of dengue without warning signs 2.Patients who get admitted at or after day 7 of fever. 3.Pediatric patients with diagnosed nephrotic syndrome, acute glomerulonephritis, acute renal failure, tubulo interstitial disease, Immune mediated nephritis. 4.Patients with associated hypoalbuminemia, metabolic disorders, trauma, malignant disease, vascular problems, acute hepatitis, acute pancreatitis

Design outcomes

Primary

MeasureTime frame
Spot urine albumin creatinine ratio Gall bladder wall thickness (higher or lower) Timepoint: Spot urine albumin creatinine ratio: at admission, and on day 7 Gall bladder wall thickness (higher or lower): between day 3 and 6 of thickness

Secondary

MeasureTime frame
1.The association of urine albumin creatinine ratio with laboratory parameters (Hematocrit and platelet count) 2.The association of gall bladder wall thickness with laboratory parameters (Hematocrit and platelet count). 3.Distribution of different patterns of gall bladder wall thickness in different severity groups of dengue . Timepoint: 1,2:The association of urine albumin creatinine ratio and gall bladder wall thickness with laboratory parameters (Hematocrit and platelet count): at admission and at discharge 3.Distribution of different patterns of gall bladder wall thickness in different severity groups of dengue: between day 3 and day 6 ofillness

Countries

India

Contacts

Public ContactDr Namratha N

UCMS and GTB hospital, Delhi

manish_2710@yahoo.com9811036569

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026