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Utility of IgG4 staining in intercellular space in pemphigus and the correlation to disease activity

Utility of IgG4 staining in intercellular space in pemphigus and its correlation to disease activity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/05/052778
Enrollment
20
Registered
2023-05-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L109- Pemphigus, unspecified

Interventions

None listed

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients attending dermatology department where study is being held with a cinical diagnosis of pemphigus

Exclusion criteria

Exclusion criteria: Patients who do not give consent for biopsy

Design outcomes

Primary

MeasureTime frame
evaluate presence of igg4 antibodies in newly diagnosed pemphigus patients, asses disease severity based on PDAI nad POLIS score, correate disease activity with presence of igg4, correlate desmoglein levels to igg4 in DIFTimepoint: first visit

Secondary

MeasureTime frame
naTimepoint: na

Countries

India

Contacts

Public ContactNandana

KMC Manipal

jenny.rao@manipal.edu9845292640

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026