TWO DOSES OF DEXMEDETOMIDINE AS AN ADJUVANT TO INTRATHECAL HYPERBARIC ROPIVACAINE.

EFFICACY OF TWO DOSES OF DEXMEDETOMIDINE AS AN ADJUVANT TO INTRATHECAL HYPERBARIC ROPIVACAINE IN LOWER LIMB SURGERIES â?? A RANDOMIZED CONTROLLED TRIAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/052743

Enrollment

Registered

2023-05-17

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M810- Age-related osteoporosis without current pathological fracture Health Condition 2: O- Medical and Surgical Health Condition 3: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Different doses of Dexmedetomidine.: GROUP Aâ?? Ropivacaine with 10mcg of dexmedetomidine Duration- 0,2,4,6,12 hours Control Intervention1: Different doses of Dexmedetomidine.: GROUP B-

Eligibility

Inclusion criteria

Inclusion criteria: 1.American society of Anaesthesiologist (ASA) Physical Status I and II posted for elective lower limb surgeries. 2.Patients of age 18-60 years of either sex.

Exclusion criteria

Exclusion criteria: 1.History of allergy to the drugs used in the study like ropivacaine,dexmedetomidine. 2.pregnant women 3.deformity in spine. 4.patients with sinus bradycardia

Design outcomes

Primary

Measure	Time frame
â?¢. Postoperative VAS score. Timepoint: 2,4,6,8,12 hours	—

Secondary

Measure	Time frame
1.The incidence of hypotension and bradycardia intraoperatively. 2. Time taken for onset of sensory component by using the cold swab test till the loss of sensations.Timepoint: 2HRS,4HRS,6HRS,12HRS.	—

Countries

India

Contacts

Public ContactCHANDINI MISHRA

KALINGA INSTITUTE OF MEDICAL SCIENCES

trajmohan.rao@kims.ac.in9701185818

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026