Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: comparative study to evaluate Vasodilatory effect of Desflurane vs Sevoflurane using Perfusion Index
: Anaesthesia will be induced using either Desflurane or Sevoflurane depending on
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: sixty adults of either sex, age group (18yr-65yr) belonging to the American Society of Anaesthesiologist (ASA) Physical status I and II adults scheduled for elective surgery under GA
Exclusion criteria
Exclusion criteria: 1.Receiving any medications that may affect vascular tone (eg vasoactive drugs, such as calcium channel blockers or angiotensin receptor blockers) 2.Cardiovascular or peripheral vascular disease (e.g. Diabetic vasculopathy or Raynaudâ??s disease) 3.Medications that may affect sympathetic or parasympathetic tone(e.g. beta blockers or anticholinergics) 4.Diabetes mellitus 5.Any neurological or psychiatric diseases, including history of, or treatment for, substance abuse, anxiety, or depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perfusion index will be the primary outcome for the study.Timepoint: Baseline Perfusion index will be noted and then continuously recorded every minute for 20 min ,after induction of anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure. Timepoint: Baseline HR, PI, SBP, DBP and MAP will be noted and then continuously recorded every minute for 20 min ,after induction of anaesthesia. | — |
Countries
India
Contacts
Public ContactDr Gunjan Dhawan
Dayanand Medical College and Hospital
Outcome results
None listed