Health Condition 1: L814- Other melanin hyperpigmentation
Conditions
Interventions
Intervention1: Microneedling and Intradermal injection: Microneedling and Intradermal injection at monthly intervals 0,4,8,12 weeks
Control Intervention1: Tranexamic acid micro needling and intraderma
Sponsors
AARUPADAI VEEDU MEDICAL COLLEGE,PONDICHERRY
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with Epidermal/Dermal /Mixed type of melasma 2.Patients willing for consent, study and follow up
Exclusion criteria
Exclusion criteria: 1.Pregnancy 2,Patients on hormone replacement therapy 3.Patients on contraceptive pills 4.Patients on anticoagulants 5.Allergic to drugs under the study 6.Non compliant patients 7.Patients with keloidal or Hypertrophic scar tendency 8.Patients with the history of depigmenting treatment in the past 1 month 9.Moderate to severe acne vulgaris on face 10.History of Herpes infections, Warts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Melasma Area and Severity Index (Modified MASI) score: Primary outcome to assess treatment response.Timepoint: At baseline,4weeks, 8weeks & 12 weeks and followed up for further 2 months at monthly intervals. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical improvement assessed based on photographic documentTimepoint: At baseline, 4weeks, 8weeks & 12 weeks and followed up for further 2 months at monthly intervals. ;Patient global assessment scale andTimepoint: At baseline, 4weeks, 8weeks & 12 weeks and followed up for further 2 months at monthly intervals. | — |
Countries
India
Contacts
Public ContactSRIJHA M
Aarupadai veedu medical college,Pondicherry
Outcome results
None listed