Comparative evaluation of effectiveness of titanium platelet rich fibrin membrane and collagen membrane combined with xenograft in the treatment of mandibular class II furcation defects

Comparative evaluation of effectiveness of titanium platelet rich fibrin (T-PRF) membrane and collagen membrane combined with xenograft in the treatment of mandibular class II furcation defects â??A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/052595

Enrollment

Registered

2023-05-12

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: T-PRF with xenograft (Test group): Titanium prepared plasma rich protein with xenograft in test group will be used in mandibular class II furcation defects. Evaluation will be done aft

Eligibility

Inclusion criteria

Inclusion criteria: 1.Class II furcation defect. 2. Systematically Healthy patients. 3. Horizontal probing depth 3-6mm 4. Verticle probing depth 3mm.

Exclusion criteria

Exclusion criteria: 1) Patients not adhering for continuance of periodontal maintenance programme. 2) Patients having a habit of smoking or consuming tobacco. 3) Patients having mobility in the selected tooth. 4) Allergic reactions to the graft material which will be using for procedure, local anaesthetics, chlorhexidine content, antibiotics drugs, or analgesics. 5) Any earlier or previous periodontal regeneration procedures performed into chosen location or site. 6) Females who are pregnant or childbearing or nursing. 7) Infectious disease in patients like hepatitis, HIV, or tuberculosis. 8) Patients having a history of systemic illness.

Design outcomes

Primary

Measure	Time frame
radiografic bone fillTimepoint: At baseline, 3 months, 6 months	—

Secondary

Measure	Time frame
Clinical attachment level and periodontal probing depthTimepoint: At baseline, 3 months, 6 months	—

Countries

India

Contacts

Public ContactRuchita Tejrao Patil

Datta meghe institute of higher education and research

drprasaddhadse@gmail.com09822689401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026