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To study the cause, symptoms, and effectiveness of treatment in patients with the Syndrome of Inappropriate Anti-Diuretic Hormone Secretion.

A Study of Syndrome of Inappropriate Anti-Diuretic Hormone Secretion: Etiology, clinical features and predictors of response to therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/05/052539
Enrollment
171
Registered
2023-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E222- Syndrome of inappropriate secretion of antidiuretic hormone

Interventions

None listed

Sponsors

Kasturba Medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Euvolemia- assessed clinically Serum sodium Serum osmolality- Urinary sodium concentration >20 mmol/L Urinary osmolality >100mOsm/kg Normal Serum Cortisol Normal thyroid function

Exclusion criteria

Exclusion criteria: Patients with hypovolemic and hypervolemic Hyponatremia Patients with Hypothyroidism Patients with Addison disease Pregnant females Psychiatry patients on antipsychiatry medications Patients on diuretics Recent alcohol binge intake

Design outcomes

Primary

MeasureTime frame
Easily measurable Lab parameters like Urine Sodium and Urine Osmolality have correlation with therapeutic response to Fluid restriction. Clinical and etiological correlation is to be determined. Timepoint: 15/02/2023 to 15/08/2024—

Secondary

MeasureTime frame
clinical and etiological corelation to be determinedTimepoint: 15/02/2023 to 15/08/2024—

Countries

India

Contacts

Public ContactAvani

Kasturba Medical College, Manipal

manjunath.hande@manipal.edu9972597655

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026