To compare the efficacy of fentanyl and paracetamol magnesium combination in decreasing the pain during sternotomy in Coronary artery bypass grafting.

Comparison between the efficacy of fentanyl and paracetamol-magnesium combination in attenuating hemodynamic response to sternotomy in patients undergoing coronary artery bypass grafting-a randomized control trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/052535

Enrollment

90

Registered

2023-05-11

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: paracetamol and magnesium: Paracetamol being a nonsteroidal anti inflammatory drug has a well established safety and analgesic profile.It decreases the perioperative opioid requirements

Sponsors

Kovai medical center and hospital

Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ejection fraction >50% ASA grade 3 and 4

Exclusion criteria

Exclusion criteria: 1.patients who are not willing 2.severe left ventricular dysfunction 3.patients who are on ionotropes 4.patients on IABP 5.patients with conduction blocks 6.patients requiring valvular replacements

Design outcomes

Primary

Measure	Time frame
To compare the effects of fentanyl and paracetamol-magnesium combination in attenuating increase in BP and heart rate in patients undergoing Coronary artery bypass graftingTimepoint: From the time of induction to 5 minutes following sternotomy	—

Secondary

Measure	Time frame
To compare the time to extubation, postoperative pain intensity and analgesia requirementsTimepoint: First 24 hours of postoperative period	—

Countries

India

Contacts

Public ContactKappian

kovai medical center and hospitals

kappianmd@gmail.com9445807241

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026